Diphacinone, a vitamin K-inhibiting rodenticide, was given 2.5 mg of diphacinone/kg of body weight orally in divided doses 2 times daily for 3 days. What is vitamin K deficiency bleeding? (2019). Vitamin K1 (5 mg/kg of body weight/day divided for several 5-day regimens) was effective in preventing bleeding diathesis in diphacinone-poisoned dogs.Vitamins K1 and K2: The emerging group of vitamins required for human health. Position Statement: Guidelines for vitamin K prophylaxis in newborns. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. We link primary sources - including studies, scientific references, and statistics - within each article and also list them in the resources section at the bottom of our articles. 42, 43 There are 2 distinct enzymatic activities capable of reducing vitamin K1 quinone to the hydroquinone form. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Vitamin K is an effective antidote for poisoning with a vitamin K antagonist. a newborn’s gut cannot produce vitamin K2 in the first few days of life Fortunately, bleeding complications are generally not serious and, if necessary, can be easily controlled by the potent antidote of coumarin congeners, vitamin.a newborn’s liver is unable to use vitamin K efficiently.vitamin K does not transfer well from the placenta to the baby.There are several reasons why newborn babies are more prone to vitamin K deficiency: having had part of the intestine removed, such as during bariatric surgery.an intestinal or biliary tract (liver, gallbladder, and bile ducts) disorder.This is known as fat malabsorption.Ĭonditions associated with fat malabsorption include: Some medical conditions can make vitamin K deficiency more likely to develop, such as conditions where the body is less able to absorb fat. take extremely high doses of vitamin A or E.Phytonadione may also be used for purposes not listed in this medication guide. Phytonadione is used to treat vitamin K deficiency, and to treat certain bleeding or blood-clotting problems caused by other medicines or medical conditions. do not get enough vitamin K from the foods they eat Phytonadione is a man-made form of vitamin K, which occurs naturally in the body.take antibiotics that interfere with vitamin K production and absorption.take blood thinners, or anticoagulants, which prevent blood clots but inhibit vitamin K activation.When it does, it is known as vitamin K deficiency bleeding or VKDB.Īdults are at an increased risk of vitamin K deficiency and the associated symptoms if they: Vitamin K deficiency is much more likely to occur in infants. Most adults obtain an adequate supply of vitamin K through the foods they eat and through what their body naturally produces.Ĭertain medications and medical conditions can reduce vitamin K production and inhibit absorption, meaning adults can become deficient. If a person has a vitamin K deficiency, that means the person’s body cannot produce enough of these proteins, increasing the risk of excessive bleeding. Blood clotting or coagulation prevents excessive bleeding internally and externally. The intestine also creates some of this vitamin.īoth vitamin K1 and vitamin K2 produce proteins that help the blood clot. Physician, Suretech Hospital & RC, Dhantoli, Nagpur, Maharashtra. ![]() vitamin K2 or menaquinone, which occurs in animal-based foods, including butter and egg yolks, and fermented foods, such as kefir. Antidote for Non Vitamin K Antagonist Oral Anticoagulants.vitamin K1, or phylloquinone, which occurs in leafy green vegetables such as spinach and kale.For all other clinical situations, this is unclear and should be avoided.Share on Pinterest Image credit: julief514/Getty Images In patients with peripheral artery disease no beneficial effect was noted for the combination therapy, perhaps with an exception of those with graft failure. Only in patients with mechanical heart valves the benefits and safety of combining aspirin with VKA therapy seems obvious. So far, decisions about the combined use of aspirin and VKA are individualized in the absence of adequate data. The variation in clinical outcomes and bleeding complications suggests that extrapolating from one indication to another may not be appropriate. ![]() However, there is no consensus about additional aspirin use in the most common indications for VKA or the use of VKAs to be added to the most common aspirin indications. Unraveling the identity of this enzyme solved the last riddle of vitamin K metabolism in blood clotting and elucidated the molecular mechanism of why vitamin K constitutes the antidote for. Based on their mode of action, it is reasonable to expect that the combination therapy of aspirin and a vitamin K antagonist (VKA) may be more beneficial in preventing (athero) thrombotic complications in high-risk patients for cardiovascular events.
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![]() JS Graphics JS Graphics JS Canvas JS Plotly JS Chart.js JS Google Chart JS D3. Now let us see simple example which uses jsondecode () of PHP in a HTML structure. JS vs jQuery jQuery Selectors jQuery HTML jQuery CSS jQuery DOM This jsondecode () function of PHP takes JSON encoded string as input and returns the value that is decoded to PHP objects which of PHP data types and if the decoding is not possible then this function returns null instead of PHP objects. JS JSON JSON Intro JSON Syntax JSON vs XML JSON Data Types JSON Parse JSON Stringify JSON Objects JSON Arrays JSON Server JSON PHP JSON HTML JSON JSONP JS AJAX AJAX Intro AJAX XMLHttp AJAX Request AJAX Response AJAX XML File AJAX PHP AJAX ASP AJAX Database AJAX Applications AJAX Examples JS Web APIs Web API Intro Web Forms API Web History API Web Storage API Web Worker API Web Fetch API Web Geolocation API JS Browser BOM JS Window JS Screen JS Location JS History JS Navigator JS Popup Alert JS Timing JS Cookies JS HTML DOM DOM Intro DOM Methods DOM Document DOM Elements DOM HTML DOM Forms DOM CSS DOM Animations DOM Events DOM Event Listener DOM Navigation DOM Nodes DOM Collections DOM Node Lists JS Async JS Callbacks JS Asynchronous JS Promises JS Async/Await ![]() JS Classes Class Intro Class Inheritance Class Static JS Functions Function Definitions Function Parameters Function Invocation Function Call Function Apply Function Bind Function Closures JS Objects Object Definitions Object Properties Object Methods Object Display Object Accessors Object Constructors Object Prototypes Object Iterables Object Sets Object Maps Object Reference JS Tutorial JS HOME JS Introduction JS Where To JS Output JS Statements JS Syntax JS Comments JS Variables JS Let JS Const JS Operators JS Arithmetic JS Assignment JS Data Types JS Functions JS Objects JS Events JS Strings JS String Methods JS String Search JS String Templates JS Numbers JS BigInt JS Number Methods JS Number Properties JS Arrays JS Array Methods JS Array Sort JS Array Iteration JS Array Const JS Dates JS Date Formats JS Date Get Methods JS Date Set Methods JS Math JS Random JS Booleans JS Comparisons JS If Else JS Switch JS Loop For JS Loop For In JS Loop For Of JS Loop While JS Break JS Iterables JS Sets JS Maps JS Typeof JS Type Conversion JS Bitwise JS RegExp JS Precedence JS Errors JS Scope JS Hoisting JS Strict Mode JS this Keyword JS Arrow Function JS Classes JS Modules JS JSON JS Debugging JS Style Guide JS Best Practices JS Mistakes JS Performance JS Reserved Words ![]() MSI is a non-profit organization and relies on the generous donations of individuals, businesses, and foundations to ensure program costs for schools are as low as possible. Continue with the dialog, this will refresh your turns. Use the red switch and press the button to grab the principal. Use the blue switch to move the claw left, and then press the button. Grab Penny’s head and press the red button. Today, we average roughly 50,000 students and adults through all of our programs combined. Head behind you to the coloured switches. In our first year, the Discovery Program served about 4,000 students. These programs include the Shoreside program, the Inland Voyage, and the Tidepool program, which takes place at Pillar Point in Half Moon Bay. In 1992 the Institute created land-based programs. The Discovery Voyage was the first program created that met with great success at the Institute's formation. As one Bay Area professor remarked at the time, "On a clear day we can see the Bay, but there is no way for my students to get their hands wet-in real water." ![]() Few opportunities existed for students to get hands-on experience with the flora and fauna of San Francisco Bay. Prior to 1970, no bridge existed between environmental concerns and education in the San Francisco Bay area. The Institute's philosophy was founded on the idea that putting students in direct physical contact with their local bay environment will help cultivate their natural sense of curiosity while enriching their understanding of science and fostering a responsibility to protect their environment. Creature Feature: Before You Go Into The Nugget Cave To Meet Lily And Billy, Go Behind The Playground And Grab The Green Flower. ![]() The Marine Science Institute was founded in 1970, around the time that the issue of water resources was becoming a major concern for many Bay Area inhabitants. Utkarsh Ambudkar as Rakesh Madhava, a Theranos engineer and Holmes' former TA at Robertson's research group.Bill Irwin as Channing Robertson, Holmes' chemical engineering professor at Stanford who becomes Theranos' first board member.Mary Lynn Rajskub as Lorraine Fuisz, Richard's wife who behaves deferentially towards Noel.Macy as Richard Fuisz, the Holmes' family acquaintance with a history of healthcare patents Michel Gill as Chris Holmes, Elizabeth's father, a former Enron employee.Elizabeth Marvel as Noel Holmes, Elizabeth's mother.Naveen Andrews as Sunny Balwani, Holmes' lover and Theranos' COO.Amanda Seyfried as Elizabeth Holmes, a Stanford University dropout who goes on to found healthcare startup Theranos.The show touches on experiences that likely motivated Holmes's deceptions and lies in a linear fashion, starting from her preteens and all the way to her exposure as a fraud. The Dropout, based on the ABC Audio podcast of the same name, is a series about the rise and fall of Elizabeth Holmes and her company, Theranos. It was also nominated for Best Limited or Anthology Series or Television Film and Seyfried won Best Actress at the 80th Golden Globe Awards. ![]() At the 74th Primetime Emmy Awards, the series earned six nominations, including Outstanding Limited or Anthology Series, with Seyfried winning for Outstanding Lead Actress. It premiered on the streaming service Hulu on March 3, 2022, and received positive reviews from critics, who praised the writing and the performances of the cast, particularly Seyfried. The Dropout is the first television production to be produced by Searchlight Television. Created by Elizabeth Meriwether, the series is based on the podcast of the same name hosted by Rebecca Jarvis and produced by ABC News. The Dropout is an American biographical drama miniseries that documents the disgraced biotechnology company Theranos and its founder, Elizabeth Holmes, played by Amanda Seyfried. In this instance, all three click, with the skill of the actors getting an edge. In “meet-cute” situations like this (Arthur even explains the concept to Iris) there’s not much outcome surprise, because we know going in that a happy ending is in the cards (on page 125 of the script, with hints starting on pages 5 and 15), so hopefully the fun comes from how it’s handled by writing, direction and casting. He also has two adorable kids (thank God he’s a widower!: the script both lets Amanda off the hook and ensnares her). Over in the cozy English country cottage Iris traded, Amanda meets ‘Graham’ (Jude Law), who besides being devil handsome and charming, is Iris’s brother. Iris is astounded at Amanda’s luxury digs in Brentwood, and she befriends film composer ‘Miles’ (Jack Black) and elderly ‘Arthur Abbott (Eli Wallach), a revered screenwriter, someone who knows his characters. Each have been left adrift by their unfaithful boyfriends, and both need an escape from the scenes of the heart crimes. ![]() ‘Iris’ (Kate Winslet), Londoner and columnist, and ‘Amanda’ (Cameron Diaz), L.A.-based producer of movie trailers, meet online and decide to do a temporary house swap over the Christmas holidays. ![]() THE HOLIDAY, written, produced and directed by hitmaker Nancy Meyers for the end-of-year festive slate of 2006, is a pleasing rom-com entry, patently unsurprising in how it all ends up, and at 135 minutes, pushing it by 15 or 20, but it’s a very easy break to take, thanks mostly to the adept, personable and attractive stars. ![]() Through out house of Hades and at the end of blood of Olympus,it is said that Nico has a crush on Percy,though he gives up that dream and goes to Will Solace,the son of Apollo,and in trials of Apollo they are seen as a couple. Later in the Heroes of Olympus series,he captured captured by giants though he survived. Nico goes back to the camp and finds a new hades cabin has been built for him and all the other minor gods and goddess. In the end of the final book Percy makes all the gods and goddess to 'claim' all their children and make sure they have cabin's in Camp Half-blood. ![]() In the final book of the first series, he convinced Percy to bathe in the River Styx, making him invincible barring the small of his back. Several months later, he informed Percy of a plan that could lead to defeating Kronos. Nico refused to stay at Camp Half-Blood in the fourth book after noting that he was not welcomed at Camp Half-Blood he compares this to the fact that his father is not welcomed at Olympus. Nico tried multiple times to contact his sister and had difficulty contacting her, even using his dreams. For a time, he was Percy's enemy, blaming him for the fact that he had failed to protect Bianca as he had promised, but they became friends eventually. Nico has the power to raise skeletal warriors, shadow travel, and create great fissures in the ground that swallow up anyone or anything unfortunate enough to be standing on it at the time. At the time, he took great interest in a game called Mythomagic. At first Percy assumed Hades broke the oath not to have children after World War II, but Nico and his sister Bianca had been placed in the Lotus Casino, where 'time stands still' since before the oath was made. Nico di Angelo is a son of Hades, Bianca's younger brother, Hazel Levesque half-brother, Percy Jackson, Thalia and Jason Grace's cousin. At the end of the book, he gets to go to work for his father, Poseidon, in the Underwater forges. ![]() Also in The Sea of Monsters he was Percy's best friend and was always picked on. He is afraid of Grover while Grover is also afraid of him. He first appears in The Sea of Monsters as a homeless boy. Technically he is not a demigod, but at camp he lives in Percy's cabin, and is considered to be Percy's brother. Tyson is a Cyclops, the son of Poseidon and his mother is unknown. Not all mobile apps, products, or features are available in all regions.Requires use of a compatible FreeStyle sensor.Both LibreLinkUp and FreeStyle Libre app users must enable glucose alarms in their apps and have internet connectivity for the LibreLinkUp user to receive shared glucose alarms from Connections using FreeStyle Libre 2.Transfer of glucose data between applications depends on internet connectivity.A sensor started by the FreeStyle Libre reader will also communicate with the FreeStyle LibreLink app. The FreeStyle Libre sensor communicates with the FreeStyle Libre reader that started it or the FreeStyle LibreLink app that started it. A finger prick test using a blood glucose meter is required during times of rapidly changing glucose levels when interstitial fluid glucose levels may not accurately reflect blood glucose levels or if hypoglycaemia or impending hypoglycaemia is reported by the FreeStyle LibreLink app or when symptoms do not match the app readings. The FreeStyle LibreLink app and the FreeStyle Libre reader have similar but not identical features.Please check the website for more information about device compatibility before using the app. The FreeStyle LibreLink app is only compatible with certain mobile devices and operating systems.This device is not intended to replace self-monitoring practices as advised by a physician. The LibreLinkUp mobile app is not intended to be a primary glucose monitor: users must consult their primary device(s) and consult a healthcare professional before making any medical interpretation and therapy adjustments from the information provided by the app. ![]() Use of FreeStyle Libre-compatible apps and LibreLinkUp may require registration with LibreView. Please check for more information about device compatibility before using the app. The LibreLinkUp app is only compatible with certain mobile device and operating systems.This is all second-hand information so far, gathered on the web. Glimp can be connected to open-source app mentioned finding Libre sensors for sale with worldwide shipping on several sites: Freestyle Libre, $45, shipped worldwide ![]() The developers write that the Nexus 6P, Samsung Galaxy Core Prime, Samsung Galaxy Young and Samsung Galaxy may brick the sensor. Some specific Android phones may brick a sensor when using the Glimp app: this is mentioned by both the users and the developers. Some people write that the app gives results closer to a manual meter than the reader. The Glimp app gives slightly different readings from the Libre reader. Some people write that it is repeating the last 8 hours of its 14-day data after that, though. But the sensor keeps on broadcasting data longer and you can receive this data with a phone app. The life of the Libre sensor is limited (by software) to 14 days. The app can download, not only the last point of data on the Libre, but also every minute reading, for the past 12 hours. It is possible to use an app called Glimp to read the Libre sensor from your Android phone. If you use Glimp S for that, you can’t use a regular Libre reader afterwards. It is possible to initialize the sensor with an Android app called Glimp S, made by Italian developers (CTAPP Software). Prior to use, the sensor must be initialized, normally by the reader, so that it can start its 14-day life. NFC only works within 1.5" (4 cm): that’s how close you need to bring your phone to read the Libre sensor. For instance, you don’t get NFC in a Moto G5S+. In order to run an app to read the Libre sensor, your phone must have NFC enabled: not all Android phones do. El contenido deesta guía es el más actualizado y puede diferir de lo que se muestra en la aplicación FreeStyle Libre 2. Android and iOS phones both have NFC built-in, but Apple does not allow apps to use it (reserved for Apple Pay), so reading a Freestyle Libre sensor is only possible with an Android phone. ![]() It is possible to use the FreeStyle Libre without a reader, by using a phone app, for any phone that has NFC. Readers are locked into mg/dl or mmol/L, so, if you decide to purchase a reader, it is best to purchase one in a country which uses the unit you use. You can mix and match readers and sensors from any country. Many forum threads discuss it, so finding info is easy. I have looked into what it would take to use it. I am really interested in the Freestyle Libre, which is not available yet in the US. ![]() Boxes may not be larger than 15 x 12x 10 (legal or banker box sized). Chapel Hill, NC 27516Īll users will be limited to 2 boxes of confidential papers per appointment. ĭrop off papers at the Solid Waste Administration Office: 1207 Eubanks Rd. ![]() Thursdays – open to Orange County small businesses including not-for-profit organizations (churches and non-government organizations).Wednesdays – open to Orange County residents and Town and County employees for personal shredding.Tuesdays – open to County Departments and Town Departments.Please call (919)968-2788 or email to schedule an appointment. Shredding is available by APPOINTMENT ONLY between 8am-2pm. Note: The Shred Center is for confidential un-shredded paper only. Please call the Recycling Division at 76 with any questions or for more information.The Shred Center is a free service available to Orange County residents, Orange County small businesses, Orange County Departments, all Town of Chapel Hill, Town of Carrboro, and Town of Hillsborough employees, as well as Town departments. We ask that you pull your vehicle off to the side so others may continue through the line. You are welcome to stay and watch your documents as they are shredded. Do not place shredded paper in your curbside recycling cart. Place your shredded paper in a brown grocery bag, fold the top over, place in the mixed paper at the Recycling Center. No three-ring binders, credit cards, or CDs will be accepted. ![]() Books of checks do not need to be separated. It is not necessary to remove windows from envelopes. Papers do not need to be separated from envelopes. It is not necessary to remove paper clips, staples, or rubber bands. Saturday, November 4, 9 am to 12 pm Shredding Events Specifications & Requirements Saturday, February 4, 9 am to 12 pm Rescheduled for March 4 Stay in your vehicle, volunteers will unload and process your paper. Please load your boxes/bags in the rear of your vehicle. There is a five box limit for all paper shredding events. This event will be held at the Coon Rapids Recycling Center located at 1827 111th Avenue NW, one block east of Hanson. Paper shredders will strip-cut all documents-The City of Coon Rapids is not responsible for shared information as the result of improper shreddingĮvents will be held four times during the year on the first Saturday from 9:00 a.m.Paper only! Remove all paper clips and rubber bands, staples may be left on.Residents must shred the paper themselves, staff cannot assist.Do NOT shred magazines, calendars, greeting cards, etc.ONLY SHRED APPROPRIATE DOCUMENTS WITH PRIVATE INFORMATION.This is meant for smaller amounts of shredding, please limit to one box per visit. The Recycling Center has self-serve paper shredders that are available for use whenever the facility is open. Our mobile events for 2023 schedule are listed below. During the spring, the shredders may be out of use in the mornings when temps are still cool. Temperatures MUST be above 40 degrees for self-serve paper shredding.Updates will be posted online and on our voicemail system.May 2- and forward, shredding closed due to construction.Shred machines have been relocated onsite. Self-Serve Paper Shredding- Shredding is OPEN. ![]() No loose shredded paper will be accepted. Shredded Paper from home- MUST be bagged in PAPER bags only. ![]() ![]() You will demonstrate an ability to work independently as well as being a collaborative team member, cultural sensitivity, and people-oriented mindset. You will bring to the role experience in a management position and of managing a team of remotely located and staff with cross functional specialisms and field experience in different operating contexts. You will also directly line management to a cohort of Humanitarian Surge Team staff (HSTs). As the Deployment Manager, you will ensure safe, rapid deployment of trained, pre-cleared deployable staff to humanitarian responses and ongoing propgrammes. ![]() Strong interpersonal/human relations skillsĪbility to interact effectively and professionally with executives of the University and external organizationsĪbility to prepare and make presentationsĪbility to maintain a high level of confidentialityĪbility to operate personal computer and various softwareīachelor’s degree in business, finance or accounting required, with master’s degree preferred supplemented with five (5) years of experience with property and casualty risk programs, preferably in higher education.We are currently looking for a Deployment Manager to join our team. Knowledge of financial and accounting management Knowledge, Skills, Abilities and Personal Characteristics: Prepares insurance budgets and manages procurement of actuarial studies and other managerial reports to aid senior leadership in their decision-making processes. Recommends additional risk transfer options (including the purchase of insurance) to address exposures presented in specific contractsĬollaborates as needed on contracts and agreements for risk and compliance with the University’s policies and procedures and all applicable state and federal laws ensures all contracts and agreements have been properly vetted prior to signature serves as University liaison with third party administrators prepares written documents and correspondence conducts large and small group presentations represents the University at regional, state and national meetings establishes and maintains effective working relationships with internal and external contacts studies insurance market conditions in order to design the optimal risk financing program. Confirms insurance provisions correspond to risk tolerance of departments and suggest revisions or consultation with appropriate subject matter experts. Under administrative direction, is responsible for the day-to-day operations of the Risk Management program works as the primary liaison for internal contacts, brokers and other external contacts for Risk Management implements and oversees programs, policies and services supervises the management of University claims.ĭetermines the most effective methods for handling risk exposures and recommends mitigation strategies and options to senior management identifies and drives improvements to overall risk management processes and documentation in conjunction with various departments in the University formulates and directs the comprehensive property, casualty, and liability insurance program implements and oversees risk mitigation programs, policies and services supervises the management of University claims including worker’s compensation, property, automobile, aviation, general liability, medical professional liability and employment-practices liability.ĭevelops management reports to communicate and monitor risks to ensure that risk responses are timely and effective educates, trains, advises and coaches managers on risk related issues, policies, procedures and work instructions analyzes, plans and advises administration on the University’s comprehensive insurance coverage.ĭesigns an appropriate and efficient claims administration infrastructure for all claims oversees the investigation and administration of University property, automobile, general liability, and/or workers’ compensation claims manages and ensures data is reported into risk and claim databases performs analyses on claims history recommends and implements policies and procedures for claims handling analyzes and monitors claims data researches trends in claim activity.Ĭollaborates with various departments, including General Counsel, Business & Finance, Audit & Compliance, Provost, Office of Research, and Student Affairs to assess various types of contracts (e.g., leases, facility use agreements, license agreements, affiliation agreements, professional services contracts, etc.). ![]() Unfortunately, Syberia IIs graphics outweigh the emotional pull of its story. An original vision of the famous comic book artist and game developer Benot Sokal The continuation of the immersive story that will touch your heart Enchanting locations with countless art nouveau and steampunk elements 2010 Anuman Interactive. The original Syberia reaped equal amounts of praise for its gameplay, graphics and original story. That's his idiot savant brother Igor who keeps repeating things in the background. What hasn’t changed, though, is the series’ gorgeous aesthetic. Far and beyond, a mystical Syberia awaits their arrival. Her voyage across land and time throws all she values into question, while the deal she sets out to sign turns into a pact with destiny. Kate rings the bell, and Ivan Bourgoff comes to the door. On her expedition across Europe, traveling from Western Europe to the far reaches of Eastern Russia, she encounters a host of incredible characters and locations in her attempt to track down Hans, the genius inventor - the final key to unlock the mystery of Syberia. The original Syberia was one of the great classic adventure games. It’s not just clumps of white pixels dribbling down the screen it’s clear, individual flakes that swirl in the wind, haphazardly fluttering on the breeze. Little did she imagine when embarking on this task that her life would be turned upside down. Though it’s prettied up with the stellar graphics and adequate writing, Syberia II is a game lacking in total ambition. ![]() Kate Walker, a young ambitious lawyer from New York, is handed what seems a fairly straight forward assignment - a quick stopover to handle the sale of an old automaton factory hidden in the alpine valleys, then straight back home to the US. |
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